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Many havereported that such studies are less likely to be accepted for publication, or that, whenthey are, have extended publication delays (Easterbrook, Berlin, Gopalan, & Matthews,1991; Elman, 2006; Naylor, 1997; Stern & Simes, 1997). This covers from the 2nd to the 8th week after conception,which is referred to as the embryonic stage. A team approach is required to collect, analyze, and treat the patient accordingly.Continuous follow-up at the bedside is needed to ensure understanding of this very com-plex, challenging patient population. In particular, they discussed two approaches to including subjects in the finalanalysis of the results of the experiment: “intention-to-treat” versus “as-treated” analysis.In the intention-to-treat analysis, all of the subjects are included in the final data analy-sis regardless of whether they completed the treatment.
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